ERCC3 Back

excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

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NCBI Description of ERCC3
ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.

Community Annotation of ERCC3 Add / Edit ERCC3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ERCC3 is highly significantly mutated in
(none)
ERCC3 is significantly mutated in
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ERCC3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ERCC3