ERAS Back

ES cell expressed Ras

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NCBI Description of ERAS
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance.

Community Annotation of ERAS Add / Edit ERAS: Annotations

No community annotations yet for ERAS.
Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ERAS is highly significantly mutated in
(none)
ERAS is significantly mutated in
(none)
ERAS is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ERAS