External References:
Wikipedia
GeneCards
HUGO
COSMIC
Google Scholar
NCBI Description of ERAP1 |
The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. |
Community Annotation of ERAP1 Add / Edit ERAP1: Annotations
No community annotations yet for ERAP1.
|
Figure notes
• "Mouse over" a mutation to see details. |
|
Click on a tumor type to see its full list of significant genes.
Data details