EPRS Back

glutamyl-prolyl-tRNA synthetase

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NCBI Description of EPRS
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.

Community Annotation of EPRS Add / Edit EPRS: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EPRS is highly significantly mutated in
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EPRS is significantly mutated in
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EPRS is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EPRS