EPN2 Back

epsin 2

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NCBI Description of EPN2
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Community Annotation of EPN2 Add / Edit EPN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EPN2 is highly significantly mutated in
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EPN2 is significantly mutated in
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EPN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EPN2