EPHX2 Back

epoxide hydrolase 2, cytoplasmic

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of EPHX2

This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.

Community Annotation of EPHX2 Add / Edit EPHX2: Annotations

No community annotations yet for EPHX2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


EPHX2 is highly significantly mutated in
EPHX2 is significantly mutated in
EPHX2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for EPHX2