EPHA7 Back

EPH receptor A7

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of EPHA7
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of EPHA7 Add / Edit EPHA7: Annotations

No community annotations yet for EPHA7.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EPHA7 is highly significantly mutated in
(none)
EPHA7 is significantly mutated in
(none)
EPHA7 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EPHA7