EPHA10 Back

EPH receptor A10

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NCBI Description of EPHA10

Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008]. ;Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008]. Sequence Note: This sequence has been modified as follows: removed 16 bp suspected to be vector contamination from the 5' end.

Community Annotation of EPHA10 Add / Edit EPHA10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EPHA10 is highly significantly mutated in
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EPHA10 is significantly mutated in
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EPHA10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for EPHA10