EPC1 Back

enhancer of polycomb homolog 1 (Drosophila)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of EPC1

This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants.

Community Annotation of EPC1 Add / Edit EPC1: Annotations

No community annotations yet for EPC1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


EPC1 is highly significantly mutated in
EPC1 is significantly mutated in
EPC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for EPC1