EPC1 Back

enhancer of polycomb homolog 1 (Drosophila)

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NCBI Description of EPC1
This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants.

Community Annotation of EPC1 Add / Edit EPC1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EPC1 is highly significantly mutated in
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EPC1 is significantly mutated in
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EPC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EPC1