EPB49 Back

erythrocyte membrane protein band 4.9 (dematin)

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NCBI Description of EPB49
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).[supplied by OMIM, Apr 2009].

Community Annotation of EPB49 Add / Edit EPB49: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EPB49 is highly significantly mutated in
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EPB49 is significantly mutated in
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EPB49 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EPB49