ENC1 Back

ectodermal-neural cortex (with BTB-like domain)

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NCBI Description of ENC1
This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of ENC1 Add / Edit ENC1: Annotations

No community annotations yet for ENC1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ENC1 is highly significantly mutated in
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ENC1 is significantly mutated in
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ENC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ENC1