EMR1 Back

egf-like module containing, mucin-like, hormone receptor-like 1

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NCBI Description of EMR1

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of EMR1 Add / Edit EMR1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EMR1 is highly significantly mutated in
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EMR1 is significantly mutated in
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EMR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for EMR1