ELMO1 Back

engulfment and cell motility 1

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NCBI Description of ELMO1
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of ELMO1 Add / Edit ELMO1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ELMO1 is highly significantly mutated in
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ELMO1 is significantly mutated in
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ELMO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ELMO1