ELMO1 Back

engulfment and cell motility 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ELMO1

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of ELMO1 Add / Edit ELMO1: Annotations

No community annotations yet for ELMO1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ELMO1 is highly significantly mutated in
ELMO1 is significantly mutated in
ELMO1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ELMO1