ELK4 Back

ELK4, ETS-domain protein (SRF accessory protein 1)

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NCBI Description of ELK4

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene.

Community Annotation of ELK4 Add / Edit ELK4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ELK4 is highly significantly mutated in
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ELK4 is significantly mutated in
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ELK4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ELK4