ELK3 Back

ELK3, ETS-domain protein (SRF accessory protein 2)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ELK3
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.

Community Annotation of ELK3 Add / Edit ELK3: Annotations

No community annotations yet for ELK3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ELK3 is highly significantly mutated in
(none)
ELK3 is significantly mutated in
(none)
ELK3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ELK3