ELAVL3 Back

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

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NCBI Description of ELAVL3
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of ELAVL3 Add / Edit ELAVL3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ELAVL3 is highly significantly mutated in
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ELAVL3 is significantly mutated in
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ELAVL3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ELAVL3