EIF4EBP3 Back

eukaryotic translation initiation factor 4E binding protein 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of EIF4EBP3
This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

Community Annotation of EIF4EBP3 Add / Edit EIF4EBP3: Annotations

No community annotations yet for EIF4EBP3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EIF4EBP3 is highly significantly mutated in
(none)
EIF4EBP3 is significantly mutated in
(none)
EIF4EBP3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EIF4EBP3