EIF4EBP2 Back

eukaryotic translation initiation factor 4E binding protein 2

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NCBI Description of EIF4EBP2
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.

Community Annotation of EIF4EBP2 Add / Edit EIF4EBP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EIF4EBP2 is highly significantly mutated in
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EIF4EBP2 is significantly mutated in
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EIF4EBP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EIF4EBP2