EGR2 Back

early growth response 2 (Krox-20 homolog, Drosophila)

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NCBI Description of EGR2
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of EGR2 Add / Edit EGR2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EGR2 is highly significantly mutated in
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EGR2 is significantly mutated in
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EGR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EGR2