EGR1 Back

early growth response 1

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NCBI Description of EGR1
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Community Annotation of EGR1 Add / Edit EGR1: Annotations

No community annotations yet for EGR1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EGR1 is highly significantly mutated in
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EGR1 is significantly mutated in
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EGR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EGR1