EFS Back

embryonal Fyn-associated substrate

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NCBI Description of EFS
The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene.

Community Annotation of EFS Add / Edit EFS: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EFS is highly significantly mutated in
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EFS is significantly mutated in
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EFS is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EFS