EEF2 Back

eukaryotic translation elongation factor 2

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NCBI Description of EEF2
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EEF2 is highly significantly mutated in
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EEF2 is significantly mutated in
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EEF2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EEF2