EEF1A2 Back

eukaryotic translation elongation factor 1 alpha 2

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NCBI Description of EEF1A2
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EEF1A2 is highly significantly mutated in
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EEF1A2 is significantly mutated in
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EEF1A2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EEF1A2