ECE2 Back

endothelin converting enzyme 2

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NCBI Description of ECE2
Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 [PubMed 11718899]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ECE2 is highly significantly mutated in
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ECE2 is significantly mutated in
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ECE2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ECE2