EBF3 Back

early B-cell factor 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of EBF3
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.

Community Annotation of EBF3 Add / Edit EBF3: Annotations

No community annotations yet for EBF3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EBF3 is highly significantly mutated in
(none)
EBF3 is significantly mutated in
(none)
EBF3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EBF3