DYRK1B Back

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

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NCBI Description of DYRK1B
DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DYRK1B is highly significantly mutated in
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DYRK1B is significantly mutated in
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DYRK1B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DYRK1B