DYNLT3 Back

dynein, light chain, Tctex-type 3

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NCBI Description of DYNLT3
This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DYNLT3 is highly significantly mutated in
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DYNLT3 is significantly mutated in
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DYNLT3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DYNLT3