dynein, light chain, Tctex-type 1

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NCBI Description of DYNLT1

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005 [PubMed 15992542]).[supplied by OMIM, Mar 2008].

Community Annotation of DYNLT1 Add / Edit DYNLT1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DYNLT1 is highly significantly mutated in
DYNLT1 is significantly mutated in
DYNLT1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DYNLT1