dynein, light chain, roadblock-type 1

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NCBI Description of DYNLRB1

This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.

Community Annotation of DYNLRB1 Add / Edit DYNLRB1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DYNLRB1 is highly significantly mutated in
DYNLRB1 is significantly mutated in
DYNLRB1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DYNLRB1