DYNC1I2 Back

dynein, cytoplasmic 1, intermediate chain 2

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NCBI Description of DYNC1I2

This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants.

Community Annotation of DYNC1I2 Add / Edit DYNC1I2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DYNC1I2 is highly significantly mutated in
DYNC1I2 is significantly mutated in
DYNC1I2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DYNC1I2