DYNC1H1 Back

dynein, cytoplasmic 1, heavy chain 1

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NCBI Description of DYNC1H1
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DYNC1H1 is highly significantly mutated in
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DYNC1H1 is significantly mutated in
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DYNC1H1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DYNC1H1