DSTN Back

destrin (actin depolymerizing factor)

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NCBI Description of DSTN
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.

Community Annotation of DSTN Add / Edit DSTN: Annotations

No community annotations yet for DSTN.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DSTN is highly significantly mutated in
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DSTN is significantly mutated in
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DSTN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DSTN