External References:
Wikipedia
GeneCards
HUGO
COSMIC
Google Scholar
NCBI Description of DST |
This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration. |
Community Annotation of DST Add / Edit DST: Annotations
No community annotations yet for DST.
|
Figure notes
• "Mouse over" a mutation to see details. |
![]() |
Click on a tumor type to see its full list of significant genes.
Data details