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dermatan sulfate epimerase

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NCBI Description of DSE

The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene.

Community Annotation of DSE Add / Edit DSE: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DSE is highly significantly mutated in
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DSE is significantly mutated in
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DSE is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DSE