DSCC1 Back

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

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NCBI Description of DSCC1
CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009].

Community Annotation of DSCC1 Add / Edit DSCC1: Annotations

No community annotations yet for DSCC1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DSCC1 is highly significantly mutated in
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DSCC1 is significantly mutated in
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DSCC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DSCC1