dihydropyrimidinase-like 5

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NCBI Description of DPYSL5

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DPYSL5 is highly significantly mutated in
DPYSL5 is significantly mutated in
DPYSL5 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DPYSL5