DPY19L2 Back

dpy-19-like 2 (C. elegans)

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NCBI Description of DPY19L2

The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9).

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DPY19L2 is highly significantly mutated in
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DPY19L2 is significantly mutated in
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DPY19L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DPY19L2