DPP9 Back

dipeptidyl-peptidase 9

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DPP9
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized.

Community Annotation of DPP9 Add / Edit DPP9: Annotations

No community annotations yet for DPP9.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DPP9 is highly significantly mutated in
(none)
DPP9 is significantly mutated in
(none)
DPP9 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DPP9