DPP7 Back

dipeptidyl-peptidase 7

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NCBI Description of DPP7

The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DPP7 is highly significantly mutated in
DPP7 is significantly mutated in
DPP7 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DPP7