DOK5 Back

docking protein 5

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NCBI Description of DOK5
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.

Community Annotation of DOK5 Add / Edit DOK5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DOK5 is highly significantly mutated in
(none)
DOK5 is significantly mutated in
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DOK5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DOK5