DOK1 Back

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DOK1

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of DOK1 Add / Edit DOK1: Annotations

No community annotations yet for DOK1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DOK1 is highly significantly mutated in
DOK1 is significantly mutated in
DOK1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DOK1