NCBI Description of DOCK6
|This gene encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2.|
Community Annotation of DOCK6 Add / Edit DOCK6: Annotations
No community annotations yet for DOCK6.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.