DOCK1 Back

dedicator of cytokinesis 1

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NCBI Description of DOCK1

This gene product binds to the SH3 domain of CRK protein. It may regulate cell surface extension and may have a role in the cell surface extension of an engulfing cell around a dying cell during apoptosis.

Community Annotation of DOCK1 Add / Edit DOCK1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DOCK1 is highly significantly mutated in
DOCK1 is significantly mutated in
DOCK1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DOCK1