DNMT1 Back

DNA (cytosine-5-)-methyltransferase 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DNMT1
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of DNMT1 Add / Edit DNMT1: Annotations

No community annotations yet for DNMT1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DNMT1 is highly significantly mutated in
(none)
DNMT1 is significantly mutated in
(none)
DNMT1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DNMT1