DND1 Back

dead end homolog 1 (zebrafish)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DND1

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

Community Annotation of DND1 Add / Edit DND1: Annotations

No community annotations yet for DND1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DND1 is highly significantly mutated in
DND1 is significantly mutated in
DND1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DND1