DNASE1L1 Back

deoxyribonuclease I-like 1

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NCBI Description of DNASE1L1

This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DNASE1L1 is highly significantly mutated in
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DNASE1L1 is significantly mutated in
(none)
DNASE1L1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DNASE1L1