DNAJC5 Back

DnaJ (Hsp40) homolog, subfamily C, member 5

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NCBI Description of DNAJC5
This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.

Community Annotation of DNAJC5 Add / Edit DNAJC5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DNAJC5 is highly significantly mutated in
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DNAJC5 is significantly mutated in
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DNAJC5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DNAJC5