DnaJ (Hsp40) homolog, subfamily B, member 6

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DNAJB6

This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.

Community Annotation of DNAJB6 Add / Edit DNAJB6: Annotations

No community annotations yet for DNAJB6.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DNAJB6 is highly significantly mutated in
DNAJB6 is significantly mutated in
DNAJB6 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DNAJB6