DnaJ (Hsp40) homolog, subfamily B, member 2

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NCBI Description of DNAJB2

This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DNAJB2 is highly significantly mutated in
DNAJB2 is significantly mutated in
DNAJB2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DNAJB2