DMC1 Back

DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)

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NCBI Description of DMC1
The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined.

Community Annotation of DMC1 Add / Edit DMC1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DMC1 is highly significantly mutated in
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DMC1 is significantly mutated in
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DMC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DMC1